Structure of PDB 4rtw Chain C Binding Site BS01
Receptor Information
>4rtw Chain C (length=57) Species:
9031
(Gallus gallus) [
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MTFVALYDYVSRTETDLSFKKGERLQIVNNTEGDWWLAHSLTTGRTGYIP
SNYVAPS
Ligand information
>4rtw Chain D (length=12) Species:
32630
(synthetic construct) [
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APPLPPRNRPRL
Receptor-Ligand Complex Structure
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PDB
4rtw
Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12
Resolution
1.24 Å
Binding residue
(original residue number in PDB)
Y90 R95 T96 E115 G116 D117 W118 N135 Y136
Binding residue
(residue number reindexed from 1)
Y7 R12 T13 E32 G33 D34 W35 N52 Y53
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:4rtw
,
PDBe:4rtw
,
PDBj:4rtw
PDBsum
4rtw
PubMed
UniProt
P00523
|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)
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