Structure of PDB 4rqz Chain C Binding Site BS01

Receptor Information
>4rqz Chain C (length=271) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYI
ITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTI
PINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQ
TDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLA
TKIMDKLIRDGRVIRGYIGIIVVNPDGPAAIQVNDLIISVDNKPALETMD
QVAEIRPGSVIPLQVTIQEYP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4rqz A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		Y258 I259 I261 M319
Binding residue
(residue number reindexed from 1)		Y217 I218 I220 M249
Enzymatic activity
Enzyme Commision number 3.4.21.107: peptidase Do.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4rqz, PDBe:4rqz, PDBj:4rqz
PDBsum4rqz
PubMed25703375
UniProtP0AEE3|DEGS_ECOLI Serine endoprotease DegS (Gene Name=degS)

[Back to BioLiP]