Structure of PDB 4qqz Chain C Binding Site BS01

Receptor Information
>4qqz Chain C (length=902) Species: 269800 (Thermobifida fusca YX) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPLDLRFWAKERGLRGKTYPLVCHSLDAAAAALVLWNEYLSPGLRDTIAS
SMETDEEHAGHCIAFWAGLHDIGKLTREFQQQIAIDLSAYPGEELSGEQR
SHAAATGKWLPFALPSLGYPNGGLVTGLVAQMLGGHHGTFHPHPSFQSRN
PLAEFGFSSPHWEKQRHALLHAVFDATGRPTPPDMLDGPTASVVCGLVIL
ADWLVSQEDFLLERLTSLPADGSASALRAHFETSLRRIPSLLDAAGLRPI
TVPPATFTESFPHLSKPNGLQASLAKHLPCLCTGPGLVLITAPMGEGKTE
AAYHVADLLGKATGRPGRFLALPTMATADQMHTRLKEYARYRVENTRSST
LALLHSMAWLNPDYAPADPFAATDWLMGRKRGLLAPWAVGTIDQALMAVL
RAKHNALRLFGLAGKVVVVDEAHAVDPYMQVLLEQLLRWLGTLDVPVVLL
SATLHHSIANSLVKAYLEGARGRRWNRSEPQPVSEVSYPGWLHVDARIGK
VTRSSDVDPLPIATTPRKPLEVRLVDVPVKEGALNRSTVLAKELTPLVKQ
GGCAAIICTTVAEAQGVYDLLSQWFATLGEDAPDLYLLHSRFPNRQRTEI
TATIVDLFGKEGAQSGRRPTRGAVLVATQVVEQSLDLDVDLMISDLAPVS
LLLQRAGRCWRHEHLGIINRPQWAKQPELVVLTPEQNAPWFPRSWTSVYP
LALLQRTYTLLRRRNGAPVQIPEDVQQLVDDVYDDDSLAEDLEADMERMG
EELAQRGLARNAVIPDPDDAEDNLNGLTEFSVLATRFGAGSVRVLCYYVD
TAGNRWLDPECTVEFPEQGTGREGRFTMADCRDLVARTIPVRMGPWASQL
TEDNHPPEAWRESFYLRDLVLIPQRVTDEGAVLPTETGGREWLLDPCKGL
IF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4qqz Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Resolution2.93 Å
Binding residue
(original residue number in PDB)
K23 D84 K87 H150 D215 W216 S219 E221 T337 M338 H371 S372 K411 T422 D424 Q425 T590 T591 V592 H620 S621 R628 T659 Q660 Q664 R729 S730 S733 V734 R828 G832 S833 R884
Binding residue
(residue number reindexed from 1)
K10 D71 K74 H137 D202 W203 S206 E208 T324 M325 H355 S356 K380 T391 D393 Q394 T559 T560 V561 H589 S590 R597 T628 Q629 Q633 R693 S694 S697 V698 R786 G790 S791 R842
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0051607 defense response to virus
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4qqz, PDBe:4qqz, PDBj:4qqz
PDBsum4qqz
PubMed25132177
UniProtQ47PJ0

[Back to BioLiP]