Structure of PDB 4qbr Chain C Binding Site BS01
Receptor Information
>4qbr Chain C (length=136) Species:
9606
(Homo sapiens) [
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SRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLEC
AYQYDDDGYQSYCTICCGGREVLMCDNNNCCRCFCVECVDLLVGPGAAQA
AIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFA
Ligand information
>4qbr Chain E (length=7) Species:
9606
(Homo sapiens) [
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ARTKQTA
Receptor-Ligand Complex Structure
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PDB
4qbr
Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
Resolution
1.902 Å
Binding residue
(original residue number in PDB)
D529 D531 Y533 Q534 G543 R544 E545 V546 L547 M548 D550 A575 I576 E578 W581
Binding residue
(residue number reindexed from 1)
D55 D57 Y59 Q60 G69 R70 E71 V72 L73 M74 D76 A101 I102 E104 W107
Enzymatic activity
Enzyme Commision number
2.1.1.-
2.1.1.37
: DNA (cytosine-5-)-methyltransferase.
External links
PDB
RCSB:4qbr
,
PDBe:4qbr
,
PDBj:4qbr
PDBsum
4qbr
PubMed
UniProt
Q9Y6K1
|DNM3A_HUMAN DNA (cytosine-5)-methyltransferase 3A (Gene Name=DNMT3A)
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