Structure of PDB 4qbq Chain C Binding Site BS01
Receptor Information
>4qbq Chain C (length=137) Species:
9606
(Homo sapiens) [
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GPLGSLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLE
CAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQ
AAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFA
Ligand information
>4qbq Chain P (length=8) Species:
9606
(Homo sapiens) [
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ARTKQTAR
Receptor-Ligand Complex Structure
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PDB
4qbq
Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
Resolution
2.406 Å
Binding residue
(original residue number in PDB)
D529 D531 G543 R544 E545 V546 M548 A575 I576 W581
Binding residue
(residue number reindexed from 1)
D56 D58 G70 R71 E72 V73 M75 A102 I103 W108
Enzymatic activity
Enzyme Commision number
2.1.1.-
2.1.1.37
: DNA (cytosine-5-)-methyltransferase.
External links
PDB
RCSB:4qbq
,
PDBe:4qbq
,
PDBj:4qbq
PDBsum
4qbq
PubMed
UniProt
Q9Y6K1
|DNM3A_HUMAN DNA (cytosine-5)-methyltransferase 3A (Gene Name=DNMT3A)
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