Structure of PDB 4pmi Chain C Binding Site BS01

Receptor Information
>4pmi Chain C (length=52) Species: 11707 (Human immunodeficiency virus type 1 (HXB3 ISOLATE)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKAVRLIKFLYQSNPPPNPEGTRQARRNRRRRWRARQRQIHSISERIRST
YL
Ligand information
>4pmi Chain A (length=40) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggaguauaugggcgcacuucggugacgguacaggcuccu
<<<<<<...<<..<<<<<....>>>.>>...>>.>>>>>>
Receptor-Ligand Complex Structure
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PDB4pmi RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev-Rev response element complex.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		R39 N40 R41 R42 R43 R44 R46 R50 R58
Binding residue
(residue number reindexed from 1)		R27 N28 R29 R30 R31 R32 R34 R38 R46
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4pmi, PDBe:4pmi, PDBj:4pmi
PDBsum4pmi
PubMed25486594
UniProtP69718|REV_HV1H3 Protein Rev (Gene Name=rev)

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