Structure of PDB 4pbp Chain C Binding Site BS01

Receptor Information
>4pbp Chain C (length=207) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FKNLSGKVLQFKTATDNSYVKLYPEKPLSLSAFTLCMRVATELPLDREVI
LFAYYTPDVDELNVWRERDGRVSLYIQSSKDAAFFRLPPLSTLQTHLCVA
WESATGLTAFWMDGRRSLHQVYRKGYSIRSGGTVVLGQDPDSYVGSFDVD
QSFVGEIANLQMWDYVLSSAQIKAVYYNQDNRVKGNVFDWDTIEYDVTGN
VLVVPDN
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4pbp Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4pbp Crystal structures for short-chain pentraxin from zebrafish demonstrate a cyclic trimer with new recognition and effector faces.
Resolution1.648 Å
Binding residue
(original residue number in PDB)		D139 D141 Q151
Binding residue
(residue number reindexed from 1)		D139 D141 Q151
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0015485 cholesterol binding
GO:0046872 metal ion binding
Biological Process
GO:0006953 acute-phase response
GO:0008150 biological_process
GO:0051607 defense response to virus
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4pbp, PDBe:4pbp, PDBj:4pbp
PDBsum4pbp
PubMed25592778
UniProtQ0IIP8|CRP_DANRE C-reactive protein (Gene Name=crp)

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