Structure of PDB 4p1w Chain C Binding Site BS01

Receptor Information
>4p1w Chain C (length=399) Species: 559295 (Lachancea thermotolerans CBS 6340) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEAVIEKLLENSRKFLTGAKLICQESNDHLTTTKLRIREWQKFQSKLHFV
LDCIQQQTKFLSEILLREGIGRNLIEEEWSQTVLVRLVNDMKFWQNEITK
MMNKLDNITNEIDQQHNSKLGDFISRDSSHILDSKLNEIPTIRKQVENIT
RQYQTMLAKVQSQLVESRMKGLRDLKLNEEFTNEADQLEQELADFLKSFT
DHFDKCSALSSRSVSPEDAQNLFEIVERDDKDLAAINSLLQDAAIDVASF
VRKVNMLLDERDADKAKMQATLSKLLTELRKHEEYISVFEGISALIQKFK
ASCLEDIRQTRNLLDFYANFERSYHNLLKEVKRRKETAAKLSQILKSCET
QLEQINTADLRERQMFLLENGNYLPETIWPDEIGSLSPLYTLNYEVRKV
Ligand information
>4p1w Chain G (length=6) Species: 559295 (Lachancea thermotolerans CBS 6340) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SSFGRL
Receptor-Ligand Complex Structure
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PDB4p1w Structural basis of starvation-induced assembly of the autophagy initiation complex.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		D208 F209 S212 H216 D243 L247 I250
Binding residue
(residue number reindexed from 1)		D194 F195 S198 H202 D229 L233 I236
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030295 protein kinase activator activity
GO:0060090 molecular adaptor activity
Biological Process
GO:0000045 autophagosome assembly
GO:0000422 autophagy of mitochondrion
GO:0006914 autophagy
GO:0034727 piecemeal microautophagy of the nucleus
Cellular Component
GO:0000407 phagophore assembly site
GO:0005737 cytoplasm
GO:0034045 phagophore assembly site membrane
GO:1990316 Atg1/ULK1 kinase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4p1w, PDBe:4p1w, PDBj:4p1w
PDBsum4p1w
PubMed24793651
UniProtC5DFJ6

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