Structure of PDB 4p0b Chain C Binding Site BS01

Receptor Information
>4p0b Chain C (length=168) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEERAFLVAREELASALRRDSGQAFSLEQLRPLLASSLPLAARYLQLDAA
RLVRCNAHRNYLNTLSTALNILEKYGRNLLSPQRPRYWRGVKFNNPVFRS
TVDAVQGGRDVLRLYGYTEEQGLSFPEGQEEPDEHQVATVTLEVLLLRTE
LSLLLQNTHPRQQALEQL
Ligand information
Receptor-Ligand Complex Structure
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PDB4p0b Binding of OTULIN to the PUB domain of HOIP controls NF-kappa B signaling.
Resolution2.7005 Å
Binding residue
(original residue number in PDB)		Y82 N85 P92 Y94 G97 N102
Binding residue
(residue number reindexed from 1)		Y75 N78 P85 Y87 G90 N95
Enzymatic activity
Enzyme Commision number 2.3.2.31: RBR-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
Cellular Component
GO:0071797 LUBAC complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4p0b, PDBe:4p0b, PDBj:4p0b
PDBsum4p0b
PubMed24726327
UniProtQ96EP0|RNF31_HUMAN E3 ubiquitin-protein ligase RNF31 (Gene Name=RNF31)

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