Structure of PDB 4knl Chain C Binding Site BS01
Receptor Information
>4knl Chain C (length=207) Species:
93061
(Staphylococcus aureus subsp. aureus NCTC 8325) [
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SLPKYKPQVNSSINDYICKNNLKAPKIEEDYTSYFPKYAYRNGVGRPEGI
VVHDTANDRSTINGEISYMKNNYQNAFVHAFVDGDRIIETAPTDYLSWGV
GAVGNPRFINVEIVHTHDYASFARSMNNYADYAATQLQYYGLKPDSAEYD
GNGTVWTHYAVSKYLGGTDHADPHGYLRSHNYSYDQLYDLINEKYLIKMG
KVAPWGT
Ligand information
>4knl Chain F (length=4) Species:
32630
(synthetic construct) [
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AEKA
Receptor-Ligand Complex Structure
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PDB
4knl
Structure-function analysis of Staphylococcus aureus amidase reveals the determinants of peptidoglycan recognition and cleavage.
Resolution
1.55 Å
Binding residue
(original residue number in PDB)
N287 A288 W310 G311 G313 H370 T380 H382
Binding residue
(residue number reindexed from 1)
N75 A76 W98 G99 G101 H158 T168 H170
Enzymatic activity
Enzyme Commision number
3.2.1.96
: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase.
3.5.1.28
: N-acetylmuramoyl-L-alanine amidase.
Gene Ontology
Molecular Function
GO:0008745
N-acetylmuramoyl-L-alanine amidase activity
Biological Process
GO:0009253
peptidoglycan catabolic process
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:4knl
,
PDBe:4knl
,
PDBj:4knl
PDBsum
4knl
PubMed
24599952
UniProt
Q2FZK7
|ATL_STAA8 Bifunctional autolysin (Gene Name=atl)
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