Structure of PDB 4kgq Chain C Binding Site BS01

Receptor Information
>4kgq Chain C (length=167) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFW
NYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASC
PPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALN
VPGSSSHDTLCTSTGHH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4kgq Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4kgq Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
Resolution2.27 Å
Binding residue
(original residue number in PDB)		C132 P133 A136 S159 S161
Binding residue
(residue number reindexed from 1)		C100 P101 A104 S127 S129
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4kgq, PDBe:4kgq, PDBj:4kgq
PDBsum4kgq
PubMed25087510
UniProtO95407|TNF6B_HUMAN Tumor necrosis factor receptor superfamily member 6B (Gene Name=TNFRSF6B)

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