Structure of PDB 4jol Chain C Binding Site BS01

Receptor Information
>4jol Chain C (length=60) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELN
YWIRRYSDAE
Ligand information
Receptor-Ligand Complex Structure
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PDB4jol A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
Resolution2.906 Å
Binding residue
(original residue number in PDB)		H491 E501 H504
Binding residue
(residue number reindexed from 1)		H3 E13 H16
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003714 transcription corepressor activity
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4jol, PDBe:4jol, PDBj:4jol
PDBsum4jol
PubMed23812588
UniProtQ06455|MTG8_HUMAN Protein CBFA2T1 (Gene Name=RUNX1T1)

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