Structure of PDB 4is1 Chain C Binding Site BS01

Receptor Information
>4is1 Chain C (length=52) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLER
HH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4is1 New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217.
Resolution2.1 Å
Binding residue
(original residue number in PDB)
F480 R481 Y485 H489 T492 Y506 Q510 T512 S513 Y516
Binding residue
(residue number reindexed from 1)
F10 R11 Y15 H19 T22 Y36 Q40 T42 S43 Y46
Binding affinityPDBbind-CN: Kd=25nM
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4is1, PDBe:4is1, PDBj:4is1
PDBsum4is1
PubMed23436653
UniProtO75362|ZN217_HUMAN Zinc finger protein 217 (Gene Name=ZNF217)

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