Structure of PDB 4iqj Chain C Binding Site BS01

Receptor Information
>4iqj Chain C (length=1166) Species: 271 (Thermus aquaticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKFAHLHQHTQFSLLDGAAKLQDLLKWVKETTPEDPALAMTDHGNLFGAV
EFYKKATAMGVKPIIGYEAYVAAESRFDRGYFHLTLLAKDFTGYQNLVRL
ASRAYLEGFYEKPRIDREILREHAQGLIALSGCLGAEIPQFILQDRLDLA
EARLNEDLSIFGDRFFIEIQNHGLPEQKKVNQVLKEFARKYGLGMVATND
GHYVRKEDARAHEVLLAIQSKTTLDDPERWRFPCDEFYVKTPEEMRAMLP
EAEWGDEPFDNTVEIARMCDVDLPIGDKMVYRIPRFPLPEGRTEAQYLRE
LTFLGLLRRYPDRITEAFYREVLRLLDERALAEALARVEEKAWEELRKEW
TAEAILHRALYELSVIERMGFPGYFLIVQDYINWARGHGVSVGPGRGSAA
GSLVAYAVGITNIDPLRFGLLFERFLNPERVSMPDIDTDFSDRERDRVIQ
YVRERYGEDKVAQIGTFASKAALKDVARVYGIPHKKAEELAKLIPVQFGK
PKPLQEAVVPELRAEMEKDERIRQVIEVAMRLEGLNRHASVHAAGVVIAA
EPLTDLVPLMRDQEGRPVTQYDMGAVEALGLLKMDFLGLRTLTFLDEARR
IVKESKGVELDYDRLPLDDPKTFELLSRGETKGVFQLESGGMTATVRGLK
PRRLEDIIALVSLYRPGPMEHIPTYIRRHHGQEPVSYAEFPHAEKYLRPI
LDETYGIPVYQEQIMQIASQVAGYSLGEADLLRRAMGKKRVEEMQKHRER
FVRGAKERGVPEEEANRLFDMLEAFANYGFNKSHAAAYSLLSYQTAYVKA
HYPVEFMAALLSVERHDSDKVAEYIRDARALGIPVLPPDVNRSGFDFKVV
GEEILFGLSAVKNVGEMAARAILEERERGGPFKSLGDFLKRLPEQVVNKR
ALESLVKAGALDAFGDRARLLASLEPLLRWAAETRERGRSGLVGVEEPPL
VEASPLDEITMLRYEKEALGIYVSGHPVLRYPGLREVASCTIEELSEFVR
ELPGKPKVLLSGMVEEVRFTLSDETGALEVVVFGRAYEGVSPKLKEDIPL
LVLAEVERVLAQAVWTLEEVLEAPKALEVEVDHALLDEKGVARLKSLLDE
HPGSLPVYLRVLGPFGEALFALREVRVGEEALGLLEAEGYRAYLVPDREV
FLQGNGGGPKEEVVPF
Ligand information
Receptor-Ligand Complex Structure
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PDB4iqj Structure of PolIIIalpha-Tauc-DNA complex suggests an atomic model of the replisome
Resolution3.2 Å
Binding residue
(original residue number in PDB)		E302 R304
Binding residue
(residue number reindexed from 1)		E290 R292
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4iqj, PDBe:4iqj, PDBj:4iqj
PDBsum4iqj
PubMed23478062
UniProtQ9XDH5|DPO3A_THEAQ DNA polymerase III subunit alpha (Gene Name=dnaE)

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