Structure of PDB 4hje Chain C Binding Site BS01

Receptor Information
>4hje Chain C (length=200) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTC
PVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPP
QHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSS
CMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRK
Ligand information
Receptor-Ligand Complex Structure
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PDB4hje Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion.
Resolution1.907 Å
Binding residue
(original residue number in PDB)		K120 S121 R248
Binding residue
(residue number reindexed from 1)		K29 S30 R157
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4hje, PDBe:4hje, PDBj:4hje
PDBsum4hje
PubMed23836939
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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