Structure of PDB 4g7z Chain C Binding Site BS01

Receptor Information
>4g7z Chain C (length=1111) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRE
TFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGL
IKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGR
YIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETL
ARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYV
YGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTL
RYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRE
RMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHK
RRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAA
YARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNR
IAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANR
ALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVD
GNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLAD
GPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIER
YEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVG
RTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLR
RGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVED
MPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFD
GAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGK
TPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHA
RSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKS
DDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDN
PVDIFEGLASK
Ligand information
Receptor-Ligand Complex Structure
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PDB4g7z Structural basis of transcription initiation.
Resolution3.815 Å
Binding residue
(original residue number in PDB)		K167 P170 W171 R243 Y256 L260 R266 D326 R353 L418 E421 R422 V427
Binding residue
(residue number reindexed from 1)		K160 P163 W164 R236 Y249 L253 R259 D319 R346 L411 E414 R415 V420
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4g7z, PDBe:4g7z, PDBj:4g7z
PDBsum4g7z
PubMed23086998
UniProtQ8RQE9|RPOB_THET8 DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

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