Structure of PDB 4e4e Chain C Binding Site BS01

Receptor Information
>4e4e Chain C (length=205) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVTLPDLKWDFGALEPYISGQINELHYTKHHQTFVNGFNTAVDQFQELSD
LLAKEPSPANARKMIAIQQNIKFHGGGFTNHCLFWENLAPESQGGGEPPT
GALAKAIDEQFGSLDELIKLTNTKLAGVQGSGWAFIVKNLSNGGKLDVVQ
TYNQDTVTGPLVPLVAIDAWEHAYYLQYQNKKADYFKAIWNVVNWKEASR
RFDAG
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain4e4e Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4e4e Six-coordinate manganese(3+) in catalysis by yeast manganese superoxide dismutase.
Resolution1.88 Å
Binding residue
(original residue number in PDB)		H26 H81 D168 H172
Binding residue
(residue number reindexed from 1)		H26 H81 D168 H172
Annotation score1
Enzymatic activity
Enzyme Commision number 1.15.1.1: superoxide dismutase.
Gene Ontology
Molecular Function
GO:0004784 superoxide dismutase activity
GO:0046872 metal ion binding
Biological Process
GO:0006801 superoxide metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4e4e, PDBe:4e4e, PDBj:4e4e
PDBsum4e4e
PubMed22908245
UniProtP00447|SODM_YEAST Superoxide dismutase [Mn], mitochondrial (Gene Name=SOD2)

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