Structure of PDB 4a75 Chain C Binding Site BS01

Receptor Information
>4a75 Chain C (length=87) Species: 8364 (Xenopus tropicalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPQVLRGSGHCKWFNVRMGFGFISMTSREGSPLENPVDVFVHQSKLYMEG
FRSLKEGEPVEFTFKKSSKGFESLRVTGPGGNPCLGN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4a75 The Lin28 Cold-Shock Domain Remodels Pre-Let-7 Microrna.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		W39 N41 V42 M44 G45 F46 F48 D64 F66 H68 Q69 F77 R78 S93 K95
Binding residue
(residue number reindexed from 1)		W13 N15 V16 M18 G19 F20 F22 D38 F40 H42 Q43 F51 R52 S67 K69
Binding affinityPDBbind-CN: Kd=169nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:4a75, PDBe:4a75, PDBj:4a75
PDBsum4a75
PubMed22570413
UniProtB4F6I0

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