Structure of PDB 4a25 Chain C Binding Site BS01

Receptor Information
>4a25 Chain C (length=169) Species: 131568 (Kineococcus radiotolerans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTIHDVQTTGLTQDAVTGFDASSRLNAGLQEVLVDLTALHLQGKQAHWNI
VGENWRDLHLQLDTLVEAARGFSDDVAERMRAVGGVPDARPQTVAASRIG
DVGPDEIDTRACVEAIVALVRHTVDTIRRVHDPIDAEDPASADLLHAITL
ELEKQAWMIGSENRSPRRR
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain4a25 Chain B Residue 1172 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4a25 Kineococcus Radiotolerans Dps Forms a Heteronuclear Mn-Fe Ferroxidase Center that May Explain the Mn-Dependent Protection Against Oxidative Stress.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		N55 D58
Binding residue
(residue number reindexed from 1)		N54 D57
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
GO:0016722 oxidoreductase activity, acting on metal ions
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4a25, PDBe:4a25, PDBj:4a25
PDBsum4a25
PubMed23396000
UniProtA6WG04

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