Structure of PDB 3zjc Chain C Binding Site BS01

Receptor Information

>3zjc Chain C (length=254) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGR
DLLVVDTPGLFDTKESLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEE
EQKTVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIV
KECGNRCCAFSNSKKTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYK
DTEERLKQREEVLRKIYTDQLNENIREEAERNIFKDVFNRIWKMLSEIWH
RFLS

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

3zjc Chain C Residue 1294 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3zjc Structural Insights Into the Mechanism of Gtpase Activation in the Gimap Family.
Resolution	3.15 Å
Binding residue (original residue number in PDB)	S22 T44
Binding residue (residue number reindexed from 1)	S15 T37
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity

	Biological Process
GO:0046039	GTP metabolic process

	Cellular Component
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005811	lipid droplet

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Molecular Function

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Cellular Component

External links

PDB	RCSB:3zjc, PDBe:3zjc, PDBj:3zjc
PDBsum	3zjc
PubMed	23454188
UniProt	Q8NHV1\|GIMA7_HUMAN GTPase IMAP family member 7 (Gene Name=GIMAP7)

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