Structure of PDB 3vi4 Chain C Binding Site BS01

Receptor Information
>3vi4 Chain C (length=589) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVLVGAPKANTSQPGVL
QGGAVYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEEPVEYKSLQW
FGATVRAHGSSILACAPLYSWRTEKEPLSDPVGTCYLSTDNFTRILEYAP
CRSDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQI
AESYYPEYLINLVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVA
GVPKGNLTYGYVTILNGSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLD
DLLVGAPLLMDRTPDGRPQEVGRVYVYLQHPAGIEPTPTLTLTGHDEFGR
FGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGLGSKPSQ
VLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRP
IVSASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVADSIG
FTVELQLDWQKQRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESD
KLSPIHIALNFSLDPQAPVDSHGLRPALHYQSKSRIEDK
Ligand information
Receptor-Ligand Complex Structure
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PDB3vi4 Crystal structure of alpha5beta1 integrin ectodomain: Atomic details of the fibronectin receptor
Resolution2.9 Å
Binding residue
(original residue number in PDB)
F187 Q221 S224 D227
Binding residue
(residue number reindexed from 1)
F187 Q221 S224 D227
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0008305 integrin complex

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Biological Process

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Cellular Component
External links
PDB RCSB:3vi4, PDBe:3vi4, PDBj:3vi4
PDBsum3vi4
PubMed22451694
UniProtP08648|ITA5_HUMAN Integrin alpha-5 (Gene Name=ITGA5)

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