Structure of PDB 3v79 Chain C Binding Site BS01

Receptor Information
>3v79 Chain C (length=424) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVY
LMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCT
AKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSL
KNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFFIHL
LDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALL
DADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMIND
GASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELT
GQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQV
PVTLVRNDGIIYSTSLTFTYTPEP
Ligand information
Receptor-Ligand Complex Structure
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PDB3v79 Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes.
Resolution3.85 Å
Binding residue
(original residue number in PDB)		K50 R51 F52 K152 R178 T183 K271
Binding residue
(residue number reindexed from 1)		K40 R41 F42 K142 R168 T173 K261
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3v79, PDBe:3v79, PDBj:3v79
PDBsum3v79
PubMed22325781
UniProtQ06330|SUH_HUMAN Recombining binding protein suppressor of hairless (Gene Name=RBPJ)

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