Structure of PDB 3u7d Chain C Binding Site BS01

Receptor Information

>3u7d Chain C (length=305) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

EKVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSEN
LSLQLKPYHKPLQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVE
KQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNYESK
KHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEYKNLSTSEGVSKEMH
HLQRMFLQNCWEIPTYGAAFFTGQIFTHKVIPVYVGVNIKGLHLLNMETK
ALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKLLMKL
NGQLM

Ligand information

>3u7d Chain D (length=6) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

RRRDYF

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	3u7d Structural basis of the junctional anchorage of the cerebral cavernous malformations complex.
Resolution	2.49 Å
Binding residue (original residue number in PDB)	W464 L472 Q473 L474 K475 H478 H483 D486 E493 F640 L721
Binding residue (residue number reindexed from 1)	W45 L53 Q54 L55 K56 H59 H64 D67 E74 F221 L296

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Cellular Component
GO:0005856	cytoskeleton

View graph for
Cellular Component

External links

PDB	RCSB:3u7d, PDBe:3u7d, PDBj:3u7d
PDBsum	3u7d
PubMed	23007647
UniProt	O00522\|KRIT1_HUMAN Krev interaction trapped protein 1 (Gene Name=KRIT1)

[Back to BioLiP]