Structure of PDB 3siq Chain C Binding Site BS01

Receptor Information
>3siq Chain C (length=97) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASVVPINDLNREETRLKTFTDWPLDWLDKRQLAQTGMYFTHAGDKVKCFF
CGVEIGSWEQEDQPVPEHQRWSPNCPLLRRRTTNNVPINAEALDRIL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3siq Chain C Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3siq Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		C80 C83 H100 C107
Binding residue
(residue number reindexed from 1)		C48 C51 H68 C75
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:3siq, PDBe:3siq, PDBj:3siq
PDBsum3siq
PubMed21811237
UniProtQ24306|DIAP1_DROME Death-associated inhibitor of apoptosis 1 (Gene Name=Diap1)

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