Structure of PDB 3roo Chain C Binding Site BS01
Receptor Information
>3roo Chain C (length=271) Species:
10090
(Mus musculus) [
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GPHSLRYFVTAVSRPGLGEPRYMEVGYVDDTEFVRFDSDAENPRYEPRAR
WMEQEGPEYWERETQKAKGNEQSFRVDLRTLLGYYNQSKGGSHTIQVISG
CEVGSDGRLLRGYQQYAYDGCDYIALNEDLKTWTAADMAALITKHKWEQA
GEAERLRAYLEGTCVEWLRRYLKNGNATLLRTDSPKAHVTHHSRPEDKVT
LRCWALGFYPADITLTWQLGEELMELVETRPAGDGTFQKWASVVVPLGKE
QYYTCHVYHQGLPEPLTLRWE
Ligand information
>3roo Chain F (length=8) [
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AVYNFATM
Receptor-Ligand Complex Structure
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PDB
3roo
Nitro-tyrosination of the immunodominant LCMV epitope gp34-41 alters both its capacity to stabilize H-2Kb and the molecular surface of the MHC complex, affecting TCR recognition
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 N70 F74 D77 L81 Y84 S99 Q114 Y116 Y123 T143 K146 E152 R155 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 N70 F74 D77 L81 Y84 S99 Q114 Y116 Y123 T143 K146 E152 R155 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3roo
,
PDBe:3roo
,
PDBj:3roo
PDBsum
3roo
PubMed
UniProt
P01901
|HA1B_MOUSE H-2 class I histocompatibility antigen, K-B alpha chain (Gene Name=H2-K1)
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