Structure of PDB 3p37 Chain C Binding Site BS01
Receptor Information
>3p37 Chain C (length=220) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
HLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSL
MKKITLLKYFRNYMSEHLLKAGANITPREELARLPYLRTWFRTRSAIILH
LSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCK
ELASRLRYARTMVDKLLSSR
Ligand information
>3p37 Chain F (length=9) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
FDPPLHSTA
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
3p37
From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
Resolution
2.38 Å
Binding residue
(original residue number in PDB)
K413 W414 V415 D416 Y417 Y481 Y485 H489 L490 H538 K540
Binding residue
(residue number reindexed from 1)
K41 W42 V43 D44 Y45 Y109 Y113 H117 L118 H164 K166
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:3p37
,
PDBe:3p37
,
PDBj:3p37
PDBsum
3p37
PubMed
21472932
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
[
Back to BioLiP
]
