Structure of PDB 3obv Chain C Binding Site BS01

Receptor Information
>3obv Chain C (length=322) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ESSRSAMMYIQELRSGLRDMHLLSCLESLRVSLNNNPVSWVQTFGAEGLA
SLLDILKRLHDEKEETSGNYDSRNQHEIIRCLKAFMNNKFGIKTMLETEE
GILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTERAEM
DEVERFQPLLDGLKSGTSIALKVGCLQLINALITPAEELDFRVHIRSELM
RLGLHQVLQELREIENEDMKVQLCVFDEQGDEDFFDLKGRLDDIRMEMDD
FGEVFQIILNTVKDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECVS
QIVLHKNGTDPDFKCRHLQIDI
Ligand information
Ligand IDFRU
InChIInChI=1S/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1
InChIKeyRFSUNEUAIZKAJO-ARQDHWQXSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04OC1C(O)C(OC1(O)CO)CO
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@](O1)(CO)O)O)O)O
CACTVS 3.341OC[CH]1O[C](O)(CO)[CH](O)[CH]1O
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)(CO)O)O)O)O
CACTVS 3.341OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O
FormulaC6 H12 O6
Namebeta-D-fructofuranose;
beta-D-fructose;
D-fructose;
fructose
ChEMBLCHEMBL604608
DrugBank
ZINCZINC000001529270
PDB chain3obv Chain M Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3obv Crystal structure of the Formin mDia1 in autoinhibited conformation.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		R285 H324
Binding residue
(residue number reindexed from 1)		R155 H194
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0031267 small GTPase binding
Biological Process
GO:0016043 cellular component organization
GO:0030036 actin cytoskeleton organization

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Molecular Function
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Biological Process
External links
PDB RCSB:3obv, PDBe:3obv, PDBj:3obv
PDBsum3obv
PubMed20927343
UniProtO08808|DIAP1_MOUSE Protein diaphanous homolog 1 (Gene Name=Diaph1)

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