Structure of PDB 3nfl Chain C Binding Site BS01
Receptor Information
>3nfl Chain C (length=89) Species:
9606
(Homo sapiens) [
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PHDNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRL
NEGDQVVLINGRDIAEHTHDQVVLFIKASCELMLLVRPN
Ligand information
>3nfl Chain G (length=5) Species:
9606
(Homo sapiens) [
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IESDV
Receptor-Ligand Complex Structure
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PDB
3nfl
Peptides Targeting the PDZ Domain of PTPN4 Are Efficient Inducers of Glioblastoma Cell Death.
Resolution
1.91 Å
Binding residue
(original residue number in PDB)
R527 F528 G529 F530 N531 V532 Q538 S545 H579 I586
Binding residue
(residue number reindexed from 1)
R17 F18 G19 F20 N21 V22 Q28 S35 H69 I76
Enzymatic activity
Enzyme Commision number
3.1.3.48
: protein-tyrosine-phosphatase.
External links
PDB
RCSB:3nfl
,
PDBe:3nfl
,
PDBj:3nfl
PDBsum
3nfl
PubMed
22000519
UniProt
P29074
|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)
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