Structure of PDB 3mhs Chain C Binding Site BS01

Receptor Information
>3mhs Chain C (length=93) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EETITIDSISNGILNNLLTTLIQDIVARETTQQQLLKTRYPDLRSYYFDP
NGSLDINGLQKQQESSQYIHCENCGRDVSANRLAAHLQRCLSR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3mhs Chain C Residue 100 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3mhs Structural insights into the assembly and function of the SAGA deubiquitinating module.
Resolution1.89 Å
Binding residue
(original residue number in PDB)		C73 C76 H88 C92
Binding residue
(residue number reindexed from 1)		C71 C74 H86 C90
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008047 enzyme activator activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006325 chromatin organization
GO:0006357 regulation of transcription by RNA polymerase II
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0000124 SAGA complex
GO:0005634 nucleus
GO:0046695 SLIK (SAGA-like) complex
GO:0070461 SAGA-type complex
GO:0071819 DUBm complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3mhs, PDBe:3mhs, PDBj:3mhs
PDBsum3mhs
PubMed20395473
UniProtQ03067|SGF11_YEAST SAGA-associated factor 11 (Gene Name=SGF11)

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