Structure of PDB 3lcp Chain C Binding Site BS01

Receptor Information
>3lcp Chain C (length=68) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EMSPQELQLHYFKMHDYDGNNLLDGLELSTAITPLMSEDELINIIDGVLR
DDDKNNDGYIDYAEFAKS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3lcp Chain C Residue 158 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3lcp Crystal structure of the LMAN1-CRD/MCFD2 transport receptor complex provides insight into combined deficiency of factor V and factor VIII.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		D81 D83 N85 L87 E92
Binding residue
(residue number reindexed from 1)		D16 D18 N20 L22 E27
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:3lcp, PDBe:3lcp, PDBj:3lcp
PDBsum3lcp
PubMed20138881
UniProtQ8NI22|MCFD2_HUMAN Multiple coagulation factor deficiency protein 2 (Gene Name=MCFD2)

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