Structure of PDB 3kl9 Chain C Binding Site BS01
Receptor Information
>3kl9 Chain C (length=337) Species:
171101
(Streptococcus pneumoniae R6) [
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TLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGLGGIFGIKH
SEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
LLTRDGHEIPVISGPAIADIVFDGGFADKAEAESFGIRPGDTIVPDSSAI
LTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGL
RGAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLP
GMKDFLLTTAEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYI
HSHQTLYAMDDFLEAQAFLQALVKKLDRSTVDLIKHY
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
3kl9 Chain C Residue 355 [
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Receptor-Ligand Complex Structure
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PDB
3kl9
Structural basis for the substrate specificity of PepA from Streptococcus pneumoniae, a dodecameric tetrahedral protease
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
H66 D181 D236
Binding residue
(residue number reindexed from 1)
H64 D164 D219
Annotation score
4
Enzymatic activity
Enzyme Commision number
3.4.11.7
: glutamyl aminopeptidase.
Gene Ontology
Molecular Function
GO:0004177
aminopeptidase activity
GO:0046872
metal ion binding
Biological Process
GO:0006508
proteolysis
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:3kl9
,
PDBe:3kl9
,
PDBj:3kl9
PDBsum
3kl9
PubMed
19914209
UniProt
Q8DNJ7
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