Structure of PDB 3jab Chain C Binding Site BS01

Receptor Information
>3jab Chain C (length=328) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHMEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTD
LNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKA
GKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIM
EHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKR
RGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAEL
VATEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVCTQLYEA
LTHVSEDCFPLLDGCRKNRQKWQALAEQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3jab Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6.
Resolution11.0 Å
Binding residue
(original residue number in PDB)
H678 I802 M804 G819 F820 F823
Binding residue
(residue number reindexed from 1)
H147 I271 M273 G288 F289 F292
Enzymatic activity
Enzyme Commision number 3.1.4.35: 3',5'-cyclic-GMP phosphodiesterase.
Gene Ontology
Molecular Function
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0008081 phosphoric diester hydrolase activity
Biological Process
GO:0007165 signal transduction

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Molecular Function

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Biological Process
External links
PDB RCSB:3jab, PDBe:3jab, PDBj:3jab
PDBsum3jab
PubMed25809480
UniProtP16586;
Q28156

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