Structure of PDB 3jab Chain C Binding Site BS01
Receptor Information
>3jab Chain C (length=328) Species:
9913
(Bos taurus) [
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SHMEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTD
LNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKA
GKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIM
EHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKR
RGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAEL
VATEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVCTQLYEA
LTHVSEDCFPLLDGCRKNRQKWQALAEQ
Ligand information
>3jab Chain D (length=17) Species:
9913
(Bos taurus) [
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EAFNHLELHELAQYGII
Receptor-Ligand Complex Structure
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PDB
3jab
Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6.
Resolution
11.0 Å
Binding residue
(original residue number in PDB)
H678 I802 M804 G819 F820 F823
Binding residue
(residue number reindexed from 1)
H147 I271 M273 G288 F289 F292
Enzymatic activity
Enzyme Commision number
3.1.4.35
: 3',5'-cyclic-GMP phosphodiesterase.
Gene Ontology
Molecular Function
GO:0004114
3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0008081
phosphoric diester hydrolase activity
Biological Process
GO:0007165
signal transduction
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Molecular Function
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Biological Process
External links
PDB
RCSB:3jab
,
PDBe:3jab
,
PDBj:3jab
PDBsum
3jab
PubMed
25809480
UniProt
P16586
;
Q28156
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