Structure of PDB 3itb Chain C Binding Site BS01

Receptor Information
>3itb Chain C (length=347) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VEAPSVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALK
ADKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLNKGVIIQ
SGNDACIALADYVAGSQESFIGLMNGYAKKLGLTNTTFQTVHGLDAPGQF
STARDMALLGKALIHDVPEEYAIHKEKEFTFNKIRQPNRNRLLWSSNLNV
DGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWG
FRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSVTIPRGQLKNLK
ASYTLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGG
Ligand information
Receptor-Ligand Complex Structure
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PDB3itb Crystal structures of penicillin-binding protein 6 from Escherichia coli.
Resolution1.8 Å
Binding residue
(original residue number in PDB)
A39 S40 G81 S82 S83 S106 G148 R194 T210 G211 T212
Binding residue
(residue number reindexed from 1)
A34 S35 G76 S77 S78 S101 G143 R189 T205 G206 T207
Enzymatic activity
Enzyme Commision number 3.4.16.4: serine-type D-Ala-D-Ala carboxypeptidase.
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0008233 peptidase activity
GO:0008658 penicillin binding
GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006508 proteolysis
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0009410 response to xenobiotic stimulus
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0030288 outer membrane-bounded periplasmic space

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Biological Process

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Cellular Component
External links
PDB RCSB:3itb, PDBe:3itb, PDBj:3itb
PDBsum3itb
PubMed19807181
UniProtP08506|DACC_ECOLI D-alanyl-D-alanine carboxypeptidase DacC (Gene Name=dacC)

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