Structure of PDB 3hsr Chain C Binding Site BS01

Receptor Information
>3hsr Chain C (length=133) Species: 426430 (Staphylococcus aureus subsp. aureus str. Newman) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVLMAIENDEK
LNIKKLGERVFLDSGTLTPLLKKLEKKDYVVRTRLQISLTEQGKAIKSPL
AEISVKVFNEFNISEREASDIINNLRNFVSKNF
Ligand information
Ligand IDBT6
InChIInChI=1S/C6H6S/c7-6-4-2-1-3-5-6/h1-5,7H
InChIKeyRMVRSNDYEFQCLF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341		Sc1ccccc1
OpenEye OEToolkits 1.5.0c1ccc(cc1)S
FormulaC6 H6 S
Namebenzenethiol
ChEMBLCHEMBL119405
DrugBank
ZINCZINC000001867127
PDB chain3hsr Chain C Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3hsr Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		K10 C13 F14
Binding residue
(residue number reindexed from 1)		K8 C11 F12
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3hsr, PDBe:3hsr, PDBj:3hsr
PDBsum3hsr
PubMed19586910
UniProtA0A0H3KA72

[Back to BioLiP]