Structure of PDB 3hb0 Chain C Binding Site BS01

Receptor Information
>3hb0 Chain C (length=259) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHMERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFN
LADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHGGVDWMRK
LAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSL
KALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTG
KESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEAL
RHALELEYL
Ligand information
Ligand IDBEF
InChIInChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
InChIKeyOGIAHMCCNXDTIE-UHFFFAOYSA-K
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[Be-](F)(F)F
ACDLabs 10.04
CACTVS 3.341		F[Be-](F)F
FormulaBe F3
NameBERYLLIUM TRIFLUORIDE ION
ChEMBL
DrugBank
ZINC
PDB chain3hb0 Chain C Residue 803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3hb0 Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D274 L275 D276 T447 T448 K480
Binding residue
(residue number reindexed from 1)		D10 L11 D12 T168 T169 K201
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Molecular Function
GO:0004725 protein tyrosine phosphatase activity
Biological Process
GO:0007275 multicellular organism development

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Molecular Function
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Biological Process
External links
PDB RCSB:3hb0, PDBe:3hb0, PDBj:3hb0
PDBsum3hb0
PubMed19858093
UniProtO00167|EYA2_HUMAN Eyes absent homolog 2 (Gene Name=EYA2)

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