Structure of PDB 3gqc Chain C Binding Site BS01

Receptor Information

>3gqc Chain C (length=423) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRQFPGQSCIMHVDMDCF
FVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQNDSVLS
RAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPYDFHAYKEVAQTLY
ETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQTKC
AASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQLVTNLPGVGH
SMESKLASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVR
TEKERKSVSAEINYGIRFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLT
LKIMVRKPGAPVETAKFGGHGICDNIARTVTLDQATDNAKIIGKAMLNMF
HTMKLNISDMRGVGIHVNQLVPT

Ligand information

>3gqc Chain I (length=12) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

atcctcccctac

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3gqc Structure of the human Rev1-DNA-dNTP ternary complex.
Resolution	2.5 Å
Binding residue (original residue number in PDB)	E571 G651 V652 G653 S655 M656 R752 T783
Binding residue (residue number reindexed from 1)	E167 G247 V248 G249 S251 M252 R348 T379

Enzymatic activity

Enzyme Commision number

2.7.7.-

Gene Ontology

	Molecular Function
GO:0003684	damaged DNA binding
GO:0003887	DNA-directed DNA polymerase activity

	Biological Process
GO:0006281	DNA repair

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Molecular Function

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Biological Process

External links

PDB	RCSB:3gqc, PDBe:3gqc, PDBj:3gqc
PDBsum	3gqc
PubMed	19464298
UniProt	Q9UBZ9\|REV1_HUMAN DNA repair protein REV1 (Gene Name=REV1)

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