Structure of PDB 3ggz Chain C Binding Site BS01

Receptor Information
>3ggz Chain C (length=182) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIPFTIKLKTCLKMCIQRLRYAQEKQQAIAKQSRRQVAQLLLTNKEQKAH
YRVETLIHDDIHIELLEILELYCELLLARVQVINDISTEEQLVKEHMDDG
INEAIRSLIYAILFVDEVKELSQLKDLMAWKINVEFVNGVIADHIDVPEK
IIKKCSPSVPKEELVDLYLKEIAKTYDVPYSK
Ligand information
>3ggz Chain G (length=16) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DEKEDKLAQRLRALRG
Receptor-Ligand Complex Structure
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PDB3ggz Structural basis of Ist1 function and Ist1-Did2 interaction in the multivesicular body pathway and cytokinesis.
Resolution3.8 Å
Binding residue
(original residue number in PDB)
R39 D64 L168 Y172 E175 T179 Y180
Binding residue
(residue number reindexed from 1)
R35 D60 L164 Y168 E171 T175 Y176
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0015031 protein transport

View graph for
Biological Process
External links
PDB RCSB:3ggz, PDBe:3ggz, PDBj:3ggz
PDBsum3ggz
PubMed19477918
UniProtP53843|IST1_YEAST Vacuolar protein sorting-associated protein IST1 (Gene Name=IST1)

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