Structure of PDB 3g8q Chain C Binding Site BS01

Receptor Information
>3g8q Chain C (length=277) Species: 2320 (Methanopyrus kandleri) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKVSLAGQTVDVKKILNEIPKRTVTAALLEGGEIVAVEEADDEHAERKLV
RRHDVEGKVVFVTARPCLYCARELAEAGVAGVVYLGRGRGLGPYYLARSG
VEVVEVHPDEPLGYDPVDRLDVLLTFGGNPYLTEEDVAARVYCLLTGRGF
DADIAPAPENLSGRVEIMVTRGDPDEAVELLKEELPVFRIRRFLISGEFD
RDELRERILEDIEPRILDPFAVRARIARAGAFSSSREAEVFIGDVLTSVG
REVNLNDPRTVVTVDVLGPRVSVGVEK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3g8q Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3g8q A cytidine deaminase edits C to U in transfer RNAs in Archaea
Resolution2.4 Å
Binding residue
(original residue number in PDB)		H44 C67
Binding residue
(residue number reindexed from 1)		H44 C67
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.4.35: tRNA(cytosine(8)) deaminase.
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0016554 cytidine to uridine editing

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Molecular Function
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Biological Process
External links
PDB RCSB:3g8q, PDBe:3g8q, PDBj:3g8q
PDBsum3g8q
PubMed19407206
UniProtQ8TWU6|CDAT8_METKA tRNA(cytosine(8)) deaminase (Gene Name=MK0935)

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