Structure of PDB 3fy4 Chain C Binding Site BS01

Receptor Information
>3fy4 Chain C (length=520) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGSLIWFRKGLRVHDNPALEYASKGSEFMYPVFVIDPHYMESDPSAFSPG
SSRAGVNRIRFLLESLKDLDSSLKKLGSRLLVFKGEPGEVLVRCLQEWKV
KRLCFEYDTDPYYQALDVKVKDYASSTGVEVFSPVSHTLFNPAHIIEKNG
GKPPLSYQSFLKVAGEPSCAKSELVMSYSSLPPIGDIGNLGISEVPSLEE
LGYKDDEQADWTPFRGGESEALKRLTKSISDKAWVANFEKPKGDPSAFLK
PATTVMSPYLKFGCLSSRYFYQCLQNIYKDVKKHTSPPVSLLGQLLWREF
FYTTAFGTPNFDKMKGNRICKQIPWNEDHAMLAAWRDGKTGYPWIDAIMV
QLLKWGWMHHLARHCVACFLTRGDLFIHWEQGRDVFERLLIDSDWAINNG
NWMWLSCSSFFYQFNRIYSPISFGKKYDPDGKYIRHFLPVLKDMPKQYIY
EPWTAPLSVQTKANCIVGKDYPKPMVLHDSASKECKRKMGEAYALNKKMD
GKVDEENLRDLRRKLQKDEH
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain3fy4 Chain C Residue 930 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3fy4 Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		E243 K246
Binding residue
(residue number reindexed from 1)		E239 K242
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Q298 W301 W329 H364 W383 W406
Catalytic site (residue number reindexed from 1) Q294 W297 W325 H360 W379 W402
Enzyme Commision number 4.1.99.13: (6-4)DNA photolyase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003914 DNA (6-4) photolyase activity
GO:0016829 lyase activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006281 DNA repair
GO:0006290 pyrimidine dimer repair
GO:0009411 response to UV

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3fy4, PDBe:3fy4, PDBj:3fy4
PDBsum3fy4
PubMed19359474
UniProtO48652|UVR3_ARATH (6-4)DNA photolyase (Gene Name=UVR3)

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