Structure of PDB 3eh2 Chain C Binding Site BS01

Receptor Information
>3eh2 Chain C (length=739) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVIEDDRNNRGTEPFVTGVRGQVPPLVTTNFLVKDQGNASPRYIRCTSYN
IPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGESGPLRCNRCKA
YMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELS
LGSYEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSL
LDFLPREGGAEESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMF
VPLLDGFLVNVNESRAVITSLLDQIPEMFTETVFVPVIQAGMEALKAAEC
AGKLFLFHTSLPIAEAPGKLKNRDDRKLINTDKEKTLFQPQTGAYQTLAK
ECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVYKYASFQVENDQERF
LSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDVELAGLDG
DKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQL
ADLYRNCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKN
CGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVT
ETNVFFYPRLLPLTESTTEPPAVRASEERLSNGDIYLLENGLNLFLWVGA
SVQQGVVQITSGLSVLPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVKQE
DKMEMLFKHFLVEDKSLSGGASYVDFLCHMHKEIRQLLS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3eh2 Chain C Residue 800 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3eh2 Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		C98 C101 C120 C123
Binding residue
(residue number reindexed from 1)		C95 C98 C117 C120
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Cellular Component
GO:0030127 COPII vesicle coat

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3eh2, PDBe:3eh2, PDBj:3eh2
PDBsum3eh2
PubMed18843296
UniProtP53992|SC24C_HUMAN Protein transport protein Sec24C (Gene Name=SEC24C)

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