Structure of PDB 3ebe Chain C Binding Site BS01

Receptor Information
>3ebe Chain C (length=177) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVGQQYHVEKFSGLRIRKPRVSSSEMERKMNGRKLIRLAQLQNKIATEKL
EEEDWVTFGVIVKKITPFSIWRLNDLKDLDKYISLFLFGDVHKEHWKTDQ
GTVIGLLNANPMGTDEVCLSVDNPQKVLLMGDAVDLGTCKARKKNGDPCT
QMVNLNDCEYCQYHVQAQYKKVSSKRA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3ebe Chain C Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ebe Structural basis for DNA binding by replication initiator mcm10.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		C381 C391 C403 H406
Binding residue
(residue number reindexed from 1)		C139 C149 C161 H164
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ebe, PDBe:3ebe, PDBj:3ebe
PDBsum3ebe
PubMed19081065
UniProtQ5EAW4|MCM10_XENLA Protein MCM10 homolog (Gene Name=mcm10)

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