Structure of PDB 3btr Chain C Binding Site BS01
Receptor Information
>3btr Chain C (length=427) Species:
10090
(Mus musculus) [
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NQGTVNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAG
LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFIS
LLASPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLS
TLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLA
DSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGN
IVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQ
IQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC
GIIEPLMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGG
LDKIEALQRHENESVYKASLNLIEKYF
Ligand information
>3btr Chain B (length=15) Species:
9606
(Homo sapiens) [
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EAGMTLGARKLKKLG
Receptor-Ligand Complex Structure
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PDB
3btr
Structural basis for the nuclear import of the human androgen receptor
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
R106 E107 W142 N146 A148 S149 G150 T151 T155 Q181 W184 N188 D192 R227 W231 R238 E266 D270
Binding residue
(residue number reindexed from 1)
R37 E38 W73 N77 A79 S80 G81 T82 T86 Q112 W115 N119 D123 R158 W162 R169 E197 D201
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3btr
,
PDBe:3btr
,
PDBj:3btr
PDBsum
3btr
PubMed
18319300
UniProt
P52293
|IMA1_MOUSE Importin subunit alpha-1 (Gene Name=Kpna2)
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