Structure of PDB 3am6 Chain C Binding Site BS01

Receptor Information
>3am6 Chain C (length=224) Species: 35845 (Acetabularia acetabulum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MADVETETGMIAQWIVFAIMAAAAIAFGVAVHFRPLKSAYYINIAICTIA
ATAYYAMAVNYQDLTMNGERQVVYARYIDWVLTTPLLLLDLIVMTKMGGV
MISWVIGADIFMIVFGILGAFEDEHKFKWVYFIAGCVMQAVLTYGMYNAT
WKDDKSPEYHSSYVSLLVFLSILWVFYPVVWAFGSGSGVLSVDNEAILMG
ILDVLAKPLFGMGCLIAHETIFKK
Ligand information
Ligand IDRET
InChIInChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
InChIKeyNCYCYZXNIZJOKI-OVSJKPMPSA-N
SMILES
SoftwareSMILES
CACTVS 3.370CC(=C\C=O)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C
ACDLabs 12.01O=C\C=C(\C=C\C=C(\C=C\C1=C(C)CCCC1(C)C)C)C
OpenEye OEToolkits 1.7.0CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=O)/C)/C
OpenEye OEToolkits 1.7.0CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=O)C)C
CACTVS 3.370CC(=CC=O)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
FormulaC20 H28 O
NameRETINAL
ChEMBLCHEMBL81379
DrugBank
ZINCZINC000004228262
PDB chain3am6 Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3am6 Crystal structure of the eukaryotic light-driven proton-pumping rhodopsin, Acetabularia rhodopsin II, from marine alga
Resolution3.2 Å
Binding residue
(original residue number in PDB)		W82 T86 M114 G118 F134 G137 C138 Q141 W178 Y181 P182 W185 K211
Binding residue
(residue number reindexed from 1)		W80 T84 M112 G116 F132 G135 C136 Q139 W174 Y177 P178 W181 K207
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0009881 photoreceptor activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0007602 phototransduction
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3am6, PDBe:3am6, PDBj:3am6
PDBsum3am6
PubMed21726566
UniProtG1K3Q0

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