Structure of PDB 3aae Chain C Binding Site BS01

Receptor Information
>3aae Chain C (length=270) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQ
YNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEAS
DPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIA
CIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQL
VSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFK
ALRRQLPVTRTKIDWNKILS
Ligand information
>3aae Chain Y (length=28) Species: 10090 (Mus musculus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ISELPSEEGRRLEHFTKLRPKRNKKQQP
Receptor-Ligand Complex Structure
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PDB3aae Two distinct mechanisms for the regulation of actin capping protein-competitive or allosteric inhibitions
Resolution3.3 Å
Binding residue
(original residue number in PDB)		N30 E31 F33 N34 R37 L46 R47 L101 K166 F168 Y199 D201
Binding residue
(residue number reindexed from 1)		N24 E25 F27 N28 R31 L40 R41 L95 K160 F162 Y193 D195
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0030036 actin cytoskeleton organization
GO:0034329 cell junction assembly
GO:0051016 barbed-end actin filament capping
GO:0051693 actin filament capping
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0008290 F-actin capping protein complex
GO:0030018 Z disc
GO:0030863 cortical cytoskeleton
GO:0071203 WASH complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3aae, PDBe:3aae, PDBj:3aae
PDBsum3aae
PubMed
UniProtP13127|CAZA1_CHICK F-actin-capping protein subunit alpha-1 (Gene Name=CAPZA1)

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