Structure of PDB 2znz Chain C Binding Site BS01

Receptor Information
>2znz Chain C (length=144) Species: 53953 (Pyrococcus horikoshii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIDKKIIKILQNDGKAPLREISKITGLAESTIHERIRKLRESGVIKKFTA
IIDPEALGYSMLAFILVKVKAGKYSEVASNLAKYPEIVEVYETTGDYDMV
VKIRTKNSEELNNFLDLIGSIPGVEGTHTMIVLKTHKETTELPI
Ligand information
Ligand IDLYS
InChIInChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+1/t5-/m0/s1
InChIKeyKDXKERNSBIXSRK-YFKPBYRVSA-O
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](CCCC[NH3+])C(O)=O
ACDLabs 10.04O=C(O)C(N)CCCC[NH3+]
OpenEye OEToolkits 1.5.0C(CC[NH3+])C[C@@H](C(=O)O)N
CACTVS 3.341N[C@@H](CCCC[NH3+])C(O)=O
OpenEye OEToolkits 1.5.0C(CC[NH3+])CC(C(=O)O)N
FormulaC6 H15 N2 O2
NameLYSINE
ChEMBL
DrugBank
ZINC
PDB chain2znz Chain C Residue 172 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2znz Interactions between the archaeal transcription repressor FL11 and its coregulators lysine and arginine.
Resolution2.39 Å
Binding residue
(original residue number in PDB)		N138 D142 T153 H154 T155
Binding residue
(residue number reindexed from 1)		N112 D116 T127 H128 T129
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0043200 response to amino acid
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2znz, PDBe:2znz, PDBj:2znz
PDBsum2znz
PubMed19004003
UniProtO59188|REG6_PYRHO HTH-type transcriptional regulator FL11 (Gene Name=fl11)

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