Structure of PDB 2zet Chain C Binding Site BS01

Receptor Information
>2zet Chain C (length=141) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLDLSTLTDEEAEHVWAVVQRDFDLRRREEERLQGLKGKIQKESSKRELL
SDTAHLNETHCARCLQPYRLLLNSRRQCLECSLFVCKSCSHAHPEEQGWL
CDPCHLARVVKIGSLEWYYQHVRARFKRFGSAKVIRSLCGR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2zet Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2zet Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		C81 C84 C107
Binding residue
(residue number reindexed from 1)		C78 C81 C104
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0031267 small GTPase binding
Biological Process
GO:0006886 intracellular protein transport

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Molecular Function
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Biological Process
External links
PDB RCSB:2zet, PDBe:2zet, PDBj:2zet
PDBsum2zet
PubMed18940604
UniProtQ91V27|MELPH_MOUSE Melanophilin (Gene Name=Mlph)

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