Structure of PDB 2y65 Chain C Binding Site BS01

Receptor Information
>2y65 Chain C (length=343) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IPAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYLFD
KVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVI
GDSVKQGIIPRIVNDIFNHIYAMEVNLEFHIKVSYYEIYMDKIRDLLDVS
KVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNE
HSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKKNINKSLSALGN
VISALADGNKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESET
KSTLDFGRRAKTVKNVVCVNEELTAEEWKRRYEKEKEKNARLK
Ligand information
>2y65 Chain W (length=13) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PQAQIAKPIRSGQ
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2y65 The Structure of the Kinesin-1 Motor-Tail Complex Reveals the Mechanism of Autoinhibition.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		F123 I126 M129 V131 N132 L133 E134 F135 H136 D154 F179 S181 D185 L224
Binding residue
(residue number reindexed from 1)		F117 I120 M123 V125 N126 L127 E128 F129 H130 D148 F173 S175 D179 L218
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:2y65, PDBe:2y65, PDBj:2y65
PDBsum2y65
PubMed21836017
UniProtP17210|KINH_DROME Kinesin heavy chain (Gene Name=Khc)

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