Structure of PDB 2x6n Chain C Binding Site BS01

Receptor Information
>2x6n Chain C (length=180) Species: 11963 (Human spumaretrovirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QKPFDKFFMDYIGPLPPSQGYLYVLVVVDGMTGFTWLYPTKAPSTSATVK
SLNVLTSIAIPRVIHSDQGAAFTSSTFAEWAKERGIHLEFSTPKVERKNS
DMKRLLTKLLVGRPTKWYDLLPVVQLAMNNTYSPVLKYTPHQLLFGIDSN
TPFANQDTLDLTREEELSLLQEIRTSLYHP
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain2x6n Chain C Residue 1197 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2x6n Structural Studies of the Catalytic Core of the Primate Foamy Virus (Pfv-1) Integrase
Resolution2.06 Å
Binding residue
(original residue number in PDB)		D128 D185
Binding residue
(residue number reindexed from 1)		D10 D67
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2x6n, PDBe:2x6n, PDBj:2x6n
PDBsum2x6n
PubMed20693659
UniProtP14350|POL_FOAMV Pro-Pol polyprotein (Gene Name=pol)

[Back to BioLiP]