Structure of PDB 2wx0 Chain C Binding Site BS01

Receptor Information
>2wx0 Chain C (length=31) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DEGAQWNCTACTFLNHPALIRCEQCEMPRHF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2wx0 Chain C Residue 1694 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2wx0 Two-Sided Ubiquitin Binding Explains Specificity of the Tab2 Nzf Domain
Resolution2.4 Å
Binding residue
(original residue number in PDB)		C670 C673 C684 C687
Binding residue
(residue number reindexed from 1)		C8 C11 C22 C25
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2wx0, PDBe:2wx0, PDBj:2wx0
PDBsum2wx0
PubMed19935683
UniProtQ9NYJ8|TAB2_HUMAN TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Gene Name=TAB2)

[Back to BioLiP]