Structure of PDB 2wax Chain C Binding Site BS01

Receptor Information
>2wax Chain C (length=165) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQ
LGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVV
INFDFPKLAETYLHRIGSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEI
KPIPSNIDKSLYVAE
Ligand information
>2wax Chain D (length=28) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
IPDTDFDFEGNLALFDKAAVFEEIDTYE
Receptor-Ligand Complex Structure
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PDB2wax Structural Basis for the Mutually Exclusive Anchoring of P Body Components Edc3 and Tral to the Dead Box Protein Ddx6/Me31B.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
Y302 Y304 Q309 H312 C313 T316 R320 K436 E439 P448 I449
Binding residue
(residue number reindexed from 1)
Y7 Y9 Q14 H17 C18 T21 R25 K140 E143 P152 I153
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
External links
PDB RCSB:2wax, PDBe:2wax, PDBj:2wax
PDBsum2wax
PubMed19285948
UniProtP26196|DDX6_HUMAN Probable ATP-dependent RNA helicase DDX6 (Gene Name=DDX6)

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